AFP (Alpha Feto Protein)

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AFP is a blood test used as a tumor marker and for pregnancy-related screening to assess fetal and liver-related conditions.

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Test Details

Also Known As

Alpha-Fetoprotein Test, AFP Tumor Marker, Serum AFP, AFP Blood Test, Fetal AFP Test

Sample Type

Blood

Gender

Male, Female

Age Group

Adults & pregnant women

Pathology

Test Code

Alpha-Fetoprotein (AFP) is a protein normally produced by the fetal liver and yolk sac during pregnancy. In adults and non-pregnant individuals, AFP levels are usually very low. Elevated AFP levels can be associated with liver diseases, particularly hepatocellular carcinoma (HCC), and certain germ cell tumors of the testes or ovaries.

During pregnancy, AFP measurement is part of antenatal screening to assess the risk of neural tube defects and certain chromosomal abnormalities in the fetus. AFP testing is also used to monitor treatment response and disease progression in patients with AFP-producing tumors. Interpretation of AFP levels depends on age, pregnancy status, and clinical context and is often combined with imaging and other tumor markers.

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Frequently Asked Questions

It is used as a tumor marker for liver cancer and germ cell tumors and for pregnancy screening.

No, it is a supportive marker and must be interpreted with imaging and clinical findings.

No fasting is required.

It may indicate liver cancer, chronic liver disease, or germ cell tumors.

To assess the risk of neural tube defects and certain fetal abnormalities.

Yes, normal AFP levels do not completely rule out liver cancer.

AFP (Alpha Feto Protein)