Cardiolipin Antibodies –IgA

Cardiolipin Antibodies – IgA are autoantibodies directed against cardiolipin, a phospholipid component of cell membranes. This test is used in the evaluation of antiphospholipid syndrome (APS), an autoimmune disorder associated with abnormal blood clotting, recurrent pregnancy loss, and certain neurological complications. While IgG and IgM cardiolipin antibodies are more commonly assessed, IgA testing is valuable in selected cases—especially when clinical suspicion of APS is high but IgG and IgM results are negative. Results should be interpreted alongside other antiphospholipid antibodies and clinical findings.