Cardiolipin Antibodies –IgG

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The Cardiolipin Antibodies IgG test detects IgG autoantibodies linked to antiphospholipid syndrome and abnormal blood clotting.

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Test Details

Also Known As

Anti-Cardiolipin IgG Antibodies, ACLA IgG Test, Cardiolipin IgG Antibody Test, Antiphospholipid Antibody IgG, aCL IgG

Sample Type

Blood

Gender

Male, Female

Age Group

Adolescents and Adults

Pathology

Test Code

Cardiolipin Antibodies – IgG are autoantibodies directed against cardiolipin, a phospholipid found in cell membranes and platelets. This test is a key investigation for antiphospholipid syndrome (APS), an autoimmune disorder characterized by recurrent blood clots, pregnancy complications (such as recurrent miscarriages), and thrombocytopenia. IgG cardiolipin antibodies are considered the most clinically significant subtype and are strongly associated with thrombotic risk. Results are interpreted alongside IgM/IgA cardiolipin antibodies, lupus anticoagulant testing, and clinical features.

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Frequently Asked Questions

It suggests antiphospholipid syndrome or increased risk of blood clots.

IgG is the most clinically significant antibody linked to thrombosis and pregnancy loss.

Yes, it is commonly used in recurrent pregnancy loss work-up.

No fasting is required.

A blood sample is analyzed using immunoassay methods such as ELISA.

Yes, positive results are usually confirmed after 12 weeks for APS diagnosis.

Cardiolipin Antibodies –IgG