Chikungunya Virus Antibody, IgM

IgM and IgG antibodies to ChikV are typically detectable 3 to 4 days and 6 to 7 days following onset of symptoms, respectively. IgM antibodies to ChikV typically remain detectable for 3 to 4 months after infection, whereas IgG antibodies to ChikV remain detectable for years.

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Positive IgM: Patients with a positive IgM test result in a single sample are classified as presumptive, recent dengue virus infections. Negative IgM: Patients with a negative IgM result between days 0–7 of illness, and absent or negative NAAT or NS1 results, are considered unconfirmed cases.

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Immunoglobulin M (IgM): Found mainly in blood and lymph fluid, this is the first antibody the body makes when it fights a new infection. Immunoglobulin E (IgE): Normally found in small amounts in the blood. There may be higher amounts when the body overreacts to allergens or is fighting an infection from a parasite.