Coomb’s Test (Indirect) (ICT)
4.6 (5 reviews)The Indirect Coomb’s Test (ICT) detects antibodies in serum that can react against red blood cells, helping identify immune-mediated hemolysis risk.
Test Details
Also Known As
Indirect Antiglobulin Test (IAT), Indirect Coomb’s Test, ICT Test, Antibody Screening Test, Serum Coomb’s Test
Sample Type
Blood
Gender
Adults and Pregnant Women
Age Group
All Ages
Categories
Pathology
Test Code
Serum (1 ml)
Coomb’s Test (Indirect), also known as Indirect Antiglobulin Test (IAT), is used to detect circulating antibodies in a patient’s serum that may bind to red blood cells. Unlike the direct Coomb’s test, ICT does not test RBCs already coated with antibodies but checks for free antibodies that can cause hemolysis.
This test is widely used in blood transfusion compatibility testing, antenatal screening in pregnancy (especially Rh incompatibility), and in diagnosing immune-mediated hemolytic anemias. A positive ICT indicates the presence of clinically significant antibodies that may cause transfusion reactions or hemolytic disease of the newborn (HDN).
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