GGT (Gamma Glutamyl Transferase)

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GGT is a blood test used to evaluate liver and bile duct function and to detect alcohol-related or drug-induced liver damage.

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Gamma-Glutamyl Transferase (GGT) is an enzyme primarily found in the liver, bile ducts, pancreas, and kidneys. It plays an important role in amino acid transport and glutathione metabolism. Elevated GGT levels are often associated with liver cell injury, bile duct obstruction, or excessive alcohol consumption.

The GGT test is commonly used along with other liver function tests such as ALT, AST, and ALP to determine the cause of abnormal liver enzymes. It is particularly helpful in differentiating liver-related causes of elevated alkaline phosphatase (ALP) and in monitoring chronic alcohol use, drug toxicity, and liver diseases such as hepatitis, fatty liver disease, and cirrhosis.

Frequently Asked Questions

It is used to assess liver health and identify bile duct disease or alcohol-related liver damage.

Fasting is usually not required, but avoiding alcohol before testing is advised.

High levels may indicate liver disease, bile duct obstruction, alcohol use, or drug toxicity.

Yes, regular or heavy alcohol consumption can significantly raise GGT levels.

Yes, GGT is commonly included in extended liver function panels.

Yes, with treatment and lifestyle changes such as stopping alcohol intake, GGT levels may normalize.