HLA-B27 (PCR)
4.6 (5 reviews)A molecular blood test to detect the HLA-B27 gene using PCR technology.
Test Details
Also Known As
HLA-B27 PCR Test, HLA-B27 Gene Test, HLA-B27 DNA Test, HLA-B27 Molecular Typing
Sample Type
Blood
Gender
Male, Female
Age Group
Adolescents and Adults
Categories
Pathology
Test Code
W B-ED TA (3 ml)
HLA-B27 (PCR) is a molecular diagnostic test that detects the presence of the HLA-B27 gene using polymerase chain reaction (PCR) technique. Unlike antigen-based methods, PCR identifies the genetic sequence responsible for HLA-B27 expression, offering high specificity and accuracy. The presence of the HLA-B27 gene is associated with an increased risk of spondyloarthropathies such as ankylosing spondylitis, reactive arthritis, and certain autoimmune uveitis conditions. This test is especially useful in cases with inconclusive serological results. PCR-based HLA-B27 testing supports early diagnosis, risk assessment, and effective clinical management.
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