TPHA (Treponema Pallidum Hemagglutination)

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TPHA is a blood test used to detect antibodies against Treponema pallidum, the bacteria responsible for syphilis.

₹449.00 ~~₹1000.00~~

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Test Details

Also Known As

TPHA Test, Treponema Pallidum Antibody Test, Syphilis Confirmatory Test, Anti-Treponema Test, TP Antibody Test

Sample Type

Venous blood (serum)

Gender

Male, Female

Age Group

All Ages

Pathology

Test Code

The TPHA (Treponema Pallidum Hemagglutination Assay) is a confirmatory serological test for syphilis that detects specific antibodies formed against Treponema pallidum.

This test works on the principle of hemagglutination, where red blood cells coated with T. pallidum antigens agglutinate in the presence of patient antibodies. TPHA becomes positive a few weeks after infection and generally remains positive for life, even after successful treatment. Therefore, it is mainly used to confirm syphilis infection and differentiate true infection from false-positive screening tests like VDRL or RPR.

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Frequently Asked Questions

It indicates current or past syphilis infection.

No, it is a confirmatory test; screening is usually done with VDRL or RPR.

Yes, TPHA often remains positive for life, even after successful treatment.

No, fasting is not required.

It may be negative in very early infection; repeat testing may be needed.

It is commonly used to confirm syphilis during antenatal screening.

TPHA (Treponema Pallidum Hemagglutination)