TTG- IgG (Tissue Transglutaminase IgG Antibody)
4.6 (5 reviews)TTG-IgG test detects IgG antibodies against tissue transglutaminase to help diagnose celiac disease, especially in IgA-deficient individuals.
Test Details
Also Known As
Anti-TTG IgG Test, Tissue Transglutaminase Antibody IgG, Celiac Disease IgG Test, TTG Antibody IgG, Gluten Sensitivity Test IgG
Sample Type
Venous blood (serum)
Gender
Male, Female
Age Group
Children and adults
Categories
Pathology
Test Code
Serum (1 ml)
The TTG-IgG (Tissue Transglutaminase IgG Antibody) test measures IgG class antibodies produced against tissue transglutaminase, an enzyme involved in intestinal mucosal repair.
This test is particularly useful in patients with selective IgA deficiency, where the standard TTG-IgA test may give false-negative results. Elevated TTG-IgG levels suggest an immune reaction to gluten and support the diagnosis of celiac disease or gluten-sensitive enteropathy. The test is commonly used alongside Total IgA and TTG-IgA for accurate evaluation and may be followed by intestinal biopsy for confirmation.
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