VDRL Test (RPR)
4.6 (5 reviews)The VDRL (RPR) test is a blood screening test used to detect syphilis by identifying non-specific antibodies produced during infection.
Test Details
Also Known As
VDRL Test, RPR Test, Syphilis Screening Test, Non-Treponemal Syphilis Test, Reagin Test
Sample Type
Blood
Gender
Male, Female
Age Group
Adolescents to elderly (as advised by physician)
Categories
Pathology
Test Code
Serum (1 ml)
The VDRL (Venereal Disease Research Laboratory) Test, commonly performed as RPR (Rapid Plasma Reagin), detects reagin antibodies formed in response to cellular damage caused by Treponema pallidum, the bacterium responsible for syphilis. It is a non-treponemal test, widely used for screening, monitoring disease activity, and assessing response to treatment. Although sensitive, it is not specific to syphilis alone and may yield false-positive results in conditions such as pregnancy, autoimmune disorders, tuberculosis, malaria, or chronic liver disease. Therefore, positive results are usually confirmed with treponemal tests like TPHA or FTA-ABS.
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